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KMID : 0363620100310050012
Journal of Korean Oriental Medicine
2010 Volume.31 No. 5 p.12 ~ p.32
Review of Randomized Controlled Trials using Herbal Remedies on Cancer Patients
Park Bong-Ky

Wang Jing-Hua
Cho Jung-Hyo
Son Chang-Gue
Abstract
Objective: This study aimed to review herbal remedy-based RCTs on cancer patients in order to produce helpful information for clinical study of herbal medicine in the future.

Methods: We collected all RCTs using herbal remedies on cancer patients from Pubmed and Cochrane databases until November 1st, 2009. Elementary information such as nation where performed, clinical question, design, randomization, double-blinding and allocation concealment were analyzed.

Results: 153 RCTs were finally selected. 119 RCTs were conduced in China while only 2 were done in Korea. The most frequent targeted cancer was lung cancer as 29 RCTs. The main clinical questions included improvement of quality of life, elongation of survival rate and regression of tumor being 83, 62 and 55 respectively. 112 RCTs used herbal remedies with western therapy. Adequate methods for randomization and allocation concealment were found in 37% and 10% of trials respectively.

Conclusions: We found that herbal remedies are used on cancer patients in aspects of both caring for the human body and tumor treatment itself. The study might provide us useful data for cancer-related clinical study using herbal remedies in the future.
KEYWORD
Herbal medicine, traditional Korean medicine, cancer, randomized clinical trial
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